Gonadotropin-Releasing Hormone (GnRH) and its ...

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Gonadotropin-Releasing Hormone (GnRH) and its Receptor in the Mouse Heart

Name:Personal
Talbott, Heather
Role :Text(marcrelator)
creator

Name:Personal
Skinner, Dr. Donal
Role :Text(marcrelator)
creator

Name:Personal
Dr. John Wu
Role :Text(marcrelator)
creator

Name:Personal
Dr. Jun Ren
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creator

Name:Personal
Dr. Feng Don
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creator

Name:Personal
Jensen, Dan
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creator

Name:Personal
Larcon, Omar
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creator

typeOfResource
still image
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PowerPoint/PDF
Origin Information Place
Laramie, Wyoming

University of Wyoming
(keyDate="yes")
9-17-2008
Place :Text
Laramie, Wyoming


2008



Language:Text
English

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born digital



abstract
The purpose of this study was to confirm preliminary data that an independent, localized GnRH system exists within the mouse heart and to examine the effects of deslorelin, a GnRH agonist, on mouse cardiac tissue. The study hypothesized that the heart contained an independent,localized GnRH system and that GnRH agonists have significant effects on cardiomyocytes, which may have negative effects on cardiac function.The results confirm that GnRH and its receptor genes are expressed in the heart. The presence of EP24.15 and the changes seen after GnRH agonist treatment indicate that GnRH might be active in the heart. More evidence is necessary before it can be concluded that GnRH acts directly on the heart
note
Subject
Heart--Physiology

Subject
Luteinizing hormone releasing hormone--Receptors

Related Item:series Title Information
McNair Scholars Program 2008

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http://hdl.handle.net/10176/wyu:84

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English
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eng

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