Polymorphism in the Human Genome caused by the ...

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Polymorphism in the Human Genome caused by the insertion of an Alu transposon

Name:Personal
McOmber, Heather
Role :Text(marcrelator)
creator

Name:Personal
Riad, Rasha
Role :Text(marcrelator)
creator

Name:Personal
Sharpe, Josh
Role :Text(marcrelator)
creator

Name:Personal
Wangeline, Dr. Ami
Role :Text(marcrelator)
contributor

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still image
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Laramie, Wyoming

University of Wyoming
(keyDate="yes")
2009-05-15

Language:Text
eng

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born digtal

abstract
The focus of this research was on an Alu insert at the pv92 locus located on Chromosome 16 in humans. Alu sequences are the most abundant short interspersed mobile elements (SINE) in the human genome, approximately 300 nucleotides in length. An examination of a polymorphism caused by the insertion of an Alu transposon at the pv92 locus for ten diverse populations was conducted using PCR and gel electrophoresis. It was found that there are significant differences in insertion frequency between some groups, suggesting patterns in migration and overall relatedness. Human chromosomes contain more than one million Alu copies, some of which are known to cause disease. Alu research offers a relatively simple method for the study of human populations in regards to relatedness and their risks for Alu implicated inherited diseases.
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From - Undergraduate Research Day 2009 - Celebration of Research - Abstracts
Subject
Alu sequences

Subject
short interspersed mobile elements

Subject
polymorphism

Related Item:series Title Information
Undergrauate Research Day 2009

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http://digital.uwyo.edu/copyright.htm
Record Information languageOfCataloging :Text(ISO639-2B)
English
:Code(ISO639-2B)
eng