Temporal Coordination of Development of Cardiac ...

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Temporal Coordination of Development of Cardiac Hypertrophy and Baroreflex Abnormalities With Iron Deficiency

Name:Personal
Almaw, Bethelhem
Role :Text(marcrelator)
creator

Name:Personal
Gandy, KC
Role :Text(marcrelator)
creator

Name:Personal
Oh, Ricky
Role :Text(marcrelator)
creator

Name:Personal
Tolhurst, Matt
Role :Text(marcrelator)
creator

Name:Personal
Chew, Dr. Bud
Role :Text(marcrelator)
contributor

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still image
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Laramie, Wyoming

University of Wyoming
(keyDate="yes")
2009-05-12

Language:Text
eng

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born digtal

abstract
Iron deficiency causes numerous cardiovascular and neurological changes. We have previously demonstrated alterations in the baroreflex (mechanism for regulation of blood pressure) with iron deficiency, involving both the sympathetic and parasympathetic nervous systems. Iron deficiency is also associated with development of cardiac hypertrophy. Prolonged iron deficiency leads to an apoptotic failing heart, but early development of hypertrophy, while not well understood with iron deficiency, is believed to be a positive adaptation, perhaps mediated by the sympathetic nervous system. We are currently examining temporal aspects of baroreflex changes and cardiac hypertrophy development with iron deficiency. We hypothesize that iron deficient, hypertrophic hearts will produce greater than normal contractile force on a Langendorff apparatus after two weeks of iron deficiency, but less than normal force after four weeks of iron deficiency. We further hypothesize that alterations in baroreflex function will occur within two weeks of iron deficiency, independent of the hypertrophy development process. Data collection is underway at time of abstract submission, with at least pilot data to be presented at the symposium.
note
From - Undergraduate Research Day 2009 - Celebration of Research - Abstracts
Subject
iron deficiency

Subject
cardiac hypertrophy

Subject
baroreflex abnormalities

Related Item:series Title Information
Undergrauate Research Day 2009

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http://digital.uwyo.edu/copyright.htm
Record Information languageOfCataloging :Text(ISO639-2B)
English
:Code(ISO639-2B)
eng