Histophilus somni myocarditis: An important cause of ...

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Histophilus somni myocarditis: An important cause of fatal disease in feeder cattle in Wyoming

Name:Personal
Allen, Travis H.
Role :Text(marcrelator)
creator

Name:Personal
Hunter, Dr. Randy
Role :Text(marcrelator)
contributor

Name:Personal
O’Toole, Dr. Donal
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contributor

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still image
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Origin Information Place
Laramie, Wyoming

University of Wyoming
(keyDate="yes")
2009-05-12

Language:Text
eng

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abstract
A large cattle backgrounding facility in eastern Wyoming identified a recurring septicemic syndrome responsible for 42.5% of all deaths between November and January 2007. This study quantified losses during the risk period (Oct 2008 – Feb 2009), and established its basis. Whole hearts and lung samples were examined from 20 animals in which the syndrome was diagnosed clinically. Tissues were examined by bacteriology, histopathology, ultrastructure and immunohistochemistry (IHC). Septicemic H. somni infection of one or both papillary muscles in left ventricular myocardium was present in 10, based on IHC and histology, and confirmed by bacterial culture in 7. Isolates had typical antigenic profiles and virulence motifs of H. somni (Dr. L. Corbeil, UC San Diego). A gene unique to H. somni was identified which encodes an integral membrane protein HS_0311(Dr. G. Andrews, UW). The gene was cloned for use in production of antibody for the IHC procedure. Ultrastructural examination established that bacterial emboli caused acute necrosis of microvascular endothelium. Other causes of death were pyelonephritis, bacterial and viral pneumonia, and brisket disease. We conclude that septicemic histophilosis with myocarditis occurs in the United States as a major cause of mortality. The disease will be overlooked unless incised hearts are examined post-mortem.
note
From - Undergraduate Research Day 2009 - Celebration of Research - Abstracts
Subject
Septicemic Histophilosis

Subject
bovine myocarditis

Related Item:series Title Information
Undergrauate Research Day 2009

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http://digital.uwyo.edu/copyright.htm
Record Information languageOfCataloging :Text(ISO639-2B)
English
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eng